As Avanos continues to invest in clinical research in the radiofrequency ablation space, we are proud to announce the publication of a large, randomized, multicentered clinical trial comparing the safety and efficacy of COOLIEF* Cooled Radiofrequency ablation to hyaluronic acid (HA) injection for the management of chronic knee pain caused by osteoarthritis.

The results to the clinical trial include:
  • At the 6-month timepoint, 71.1% of subjects receiving CRFA reported ≥ 50% pain relief compared to 37.8% of subjects receiving HA.
  • Those receiving CRFA had a 48.2% improvement in WOMAC score at 6 months, compared to 22.6% of subjects treated with HA.
  • Additionally, 72.4% of subjects in the CRFA group reported improvements in GPE compared to 40.2% in the HA group.

To read the full manuscript published in the Journal of Bone & Joint Surgery, the official journal of the American Orthopedic Association, click here.

Be sure to also stay tuned to future Avanos communications for 12-month, 18-month and 24-month timepoints from the clinical trial that will be reported in future publications.

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